Modern enterprises are required to create new business models that follow recently noticed supply chain management and service innovation in order to respond to the rapidly-changing market environment. To achieve the constant creation of innovative business, enterprises need not only traditional analysis method such as analysis for existing enterprises, but also innovative simulation method involving a virtual market environment. Such a simulation cannot be realized only by a computer-simulation, but can be realized by gaming method in which human participates in decision-making process under a competitive or collaborative virtual market environment. The simulation needs a development of methodology which examines new business model through human participation in management of virtual company, experience of iterative group decision making process in virtual world and consensus-making in real world. The Research Center for Business Simulation is aimed at practicing and evaluating the business model creation by developing a platform for business simulation in an advanced cloud computing environment.